What Is Avmacol^® Extra Strength?

Avmacol^® Extra Strength is a patented, sulforaphane-producing supplement that works in combination with Maitake mushroom extract (Grifola frondosa) to support your body’s natural detoxification process better than sulforaphane alone.¹ Avmacol^® Extra Strength provides glucoraphanin (sulforaphane glucosinolate) and active myrosinase enzyme which are the essential ingredients needed for sulforaphane production. Maitake mushroom extract has been found to provide immune support by promoting neutrophil function and natural killer cell activity.*

Sulforaphane promotes your body’s natural detoxification process for certain environmental threats found in the air you breathe, the food you eat and the water you drink, and also supports the body’s defenses against oxidative stress and cell damage.*

Avmacol^® Extra Strength may be swallowed or crushed and placed into something cold such as a smoothie, applesauce, or yogurt, as heating or cooking can inactivate the myrosinase enzyme. If a person can swallow the tablets, that is ideal.

About Avmacol^® Extra Strength

• • Contains Maitake mushroom extract (Grifola frondosa) for Immune Support*
• • Just One Tablet Daily
• • Promotes Your Body’s Natural Detoxification Process*
• • Supports Long Lasting Antioxidant Activity*
• • Vegetarian Formula
• • Gluten-Free

How Avmacol^® Extra Strength Works

Our Sulforaphane Production System^® supplies glucoraphanin (sulforaphane glucosinolate) and active myrosinase enzyme which helps promote sulforaphane production in your body. When sulforaphane enters your cells it allows for a master regulator, known as NRF2, to enter the nucleus and bind to DNA. This helps increase the production of important Phase 2 detoxifying enzymes, promoting your body’s natural detoxification process, thereby supporting the elimination of potentially harmful metabolites.*

The Maitake mushroom extract (Grifola frondosa) works in combination with sulforaphane to support your body’s natural detoxification process better than sulforaphane alone.¹ In addition, the Maitake mushroom extract found in Avmacol^® Extra Strength provides the added bonus of immune support by promoting neutrophil function and natural killer cell activity. Click here to learn more about how Avmacol^® Extra Strength works.

The Science Behind Avmacol^® Extra Strength

The combination of sulforaphane and Maitake extract supports the movement (or translocation) from the cytoplasm to the nucleus of NRF2 and increases the levels of certain Phase 2 enzymes. Click here for images of a technique called immunofluorescence which illustrate how much protein is being produced in the cell and the location of that protein.

Why Is Sulforaphane So Important?

When sulforaphane enters your cells, it helps increase the production of important Phase 2 detoxifying enzymes, promoting your body’s natural detoxification process, thereby supporting the elimination of potentially harmful metabolites. These harmful metabolites may cause damage to DNA, proteins and lipids in your cells. Read more about your body’s natural detoxification process here.

The Importance of Myrosinase

Active myrosinase enzyme is essential for the conversion of glucoraphanin (sulforaphane glucosinolate) to sulforaphane. Without this enzyme, it may not be possible to reap sulforaphane's many health-promoting benefits, which is why you’ll always find active myrosinase enzyme in the Avmacol^® brand family. Click here to learn more about the importance of having an active myrosinase enzyme.

¹In a laboratory study, treatment of RAW 264.7 cells with the combination of Maitake mushroom extract (Grifola frondosa) and sulforaphane resulted in greater induction of the expression of the Phase 2 enzyme NQO1 than either individual component alone.

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*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.